Knowhow offering
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| Title | Biomaterials from Regenerated Silk Fibroin - with applicaitons in tissue engineering, drug delivery, cosmetics etc. |
| Knowhow is available for | Various novel methods for producing 3D porous biomaterials from regenerated silk fibroin (RSF) – which has wide ranging applications in tissue engineering, wound healing bandages, drug delivery, cosmetic applications etc |
| Summary | NCL scientists have developed various processes for producing 3D porous biomaterials from regenerated silk fibroin (RSF). Our process for the accelerated gelation of RSF- resulting in a porous structure lowers the gelation time to a few hours instead of several days. The protein concentration can be between 0.1- 40%. It works in a broad pH range of 5 – 7.5, within temperatures ranging from 20-70˚C. Another process using electrospinning of RSF from an aqueous solution, forms 3D porous structures (like non-woven mats) which have various biomedical applications. Surface modification of such biomaterials for improved performance is currently under progress. |
| Advantages | • Free of microbial growth (superior performance of implants, lower toxicity)
• Shorter gelation time opens-up the potential spectrum of applications of the materials developed using this method
• Process is cheaper and faster (aqueous solution used instead of organic solvent- eliminates several intermediate steps)
• Implant that could be reproduced with great consistency and quality
• Wide range of pore sizes: 1-10 microns
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Knowhow is listed under following categories
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Knowhow from
| CSIR-NCL, Pune |
| Scientific/ engineering subject areas |
Life sciences/ biosciences & engineering ; Others |
| Investor interest categories |
Materials Technology including Nanotechnology ; Biotechnology/ Biomedical/ Health Technologies |
| Industries |
Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics ; |