| Knowhow offering | |
| Title | Continuous flow synthesis of sulphoxide compounds for use in drug formulations |
| Knowhow is available for | A process for continuous flow synthesis of pharmaceutically important sulphoxide compounds (used as Proton Pump Inhibitors- used in treating gastric disorders) with very less reaction time and easy scalability |
| Summary | Synthesis of sulphoxide compounds with reaction times of less than 1 minute. The reaction results in over 90% conversion and over 95% selectivity towards the target sulphoxide compounds (with less than 5% formation of undesired sulphone compounds) |
| Advantages | -Process capable of easy scale up -Results in high yield of the product with 95% of selectivity towards the sulphoxide compounds -Conversion rate is > 90% -The process provides an alternative solvent (to chloroform, which is a volatile solvent that evaporates at room temperature and changes the reaction mass) |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Chemical sciences & engineering ; Others |
| Investor interest categories | Biotechnology/ Biomedical/ Health Technologies ; Others |
| Industries | Pharmaceuticals, Bulk Drugs, Formulations ; |