| Knowhow offering | |
| Title | Process for the continuous flow synthesis of beta-amino crotonate (for use in anti-hypertensive drugs) |
| Knowhow is available for | A process for continuous flow synthesis of >99.98% pure beta- amino crotonates which are intermediates to calcium channel blockers (anti-hypertensive drugs) |
| Summary | A novel production process for beta-amino crotonate using a continuous mode reactor, with reduced reaction time, yet resulting in higher yield (>93%) and high-purity end-product (>99.98%). The process can be catalytic or catalysis- free : used to produce beta-amino crotonate and its analogues. |
| Advantages | -Catalytic as well as catalysis-free, continuous process -Beta amino crotonate yielded is of high purity-process provides better control on product profile - Reduced reaction time - Can be prepared from a variety of amines and beta keto esters |
| Knowhow is listed under following categories | |
| Knowhow from | CSIR-NCL, Pune |
| Scientific/ engineering subject areas | Chemical sciences & engineering ; Others |
| Investor interest categories | Others ; Others |
| Industries | Pharmaceuticals, Bulk Drugs, Formulations ; |