Knowhow offering
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| Title | Slow release hydrogel system for nutrient delivery to recombinant cell lines |
| Knowhow is available for | Slow release polymer hydrogel system to feed nutrients to cell lines for optimal selection of high protein yielding recombinant cell lines |
| Summary | Polymer hydrogel mentioned can be used for slow/extended release (ranging over a period of 2-3 days to about 2 weeks) of nutrients to desired levels that can mimic fed batch conditions and hence used to identify more reliable clones and reducing the chance of failure at large-scale culture stage. These hydrogels could be used to release various nutrients like glucose, peptides, amino acids, nucleotides, etc. |
| Advantages | • Nutrients of differing molecular weights (even lower) can be administered with controlled/slow/continuous release profiles
• A short 2 step formation procedure
• Non- cytotoxic; does not affect cell growth
• Sterilizable by gamma irradiation
• Usage leads to more reliable clone identification and less chance of failure at large scale culture stage
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Knowhow is listed under following categories
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Knowhow from
| CSIR-NCL, Pune |
| Scientific/ engineering subject areas |
Life sciences/ biosciences & engineering ; Chemical sciences & engineering |
| Investor interest categories |
Biotechnology/ Biomedical/ Health Technologies ; Materials Technology including Nanotechnology |
| Industries |
Medical Biotechnology, Biomed Products, Medical Healthcare, Diagnostics ; |