Knowhow offering
|
| Title | New Chemical Entities (NCE) for treatment of malaria and CNS disorders |
| Knowhow is available for | New Chemical Entities (NCE) that may be employed as potential leads to prepare antimalarial drugs or treatment of Central Nervous System (CNS) disorders |
| Summary | NCL scientists have discovered NCEs (substituted pyridine based alkaloids) and an efficient, fully synthetic route for their synthesis. The NCEs have antimalarial activity and some analogues could be used to treat CNS disorders. The process has an overall yield of >65%. The reaction temperature is mild (~50 â°C). |
| Advantages | • Potential drug candidates (with high anti-malarial activity) for the treatment of plasmodium and potentially, CNS disorders
• Efficient synthetic approach, with milder reaction conditions
• Higher yields in the order of >65% for all the compounds
|
|
Knowhow is listed under following categories
|
Knowhow from
| CSIR-NCL, Pune |
| Scientific/ engineering subject areas |
Chemical sciences & engineering ; Others |
| Investor interest categories |
Others ; Others |
| Industries |
Pharmaceuticals, Bulk Drugs, Formulations ; |